In the desirable Isles of Collier Preserve, this extraordinary estate home offers the rare opportunity to own possibly the finest residence in the community! Set on a sprawling half-acre, this fully furnished four-bedroom plus office and loft, seven-bath luxury home is set on a natural river with sunset views and a spectacular lanai, making it a retreat for nature lovers and refined living. Upon arrival, the paver driveway and beautiful landscaping set the stage for the grandeur that awaits. The double-door entry welcomes you to a 4,284 square-foot two-story home filled with sunlight, soaring ceilings with crown moldings and exquisite architectural details. Wood flooring flows seamlessly throughout, adding warmth and sophistication to the home's organic, modern elegance. The impressive great room has impeccable high-quality built-ins and a custom floor-to-ceiling 80-bottle wine cabinet, creating a refined atmosphere. Your dining room with a side patio glows under an opulent chandelier, surrounded by classical wainscotting. Designed for the culinary enthusiast, the kitchen features quartz counters, large island, induction cooktop, wall oven, premium stainless appliances and two beverage drawers. Under-cabinet lighting enhances the space, while a walk-in pantry with desk offers added convenience. Working from home is a pleasure in the home office with premium built-ins and custom brass hardware. The first-floor primary retreat features tray ceilings with views of the pool, river and huge backyard. Custom walk-in closets with floor-to-ceiling built-ins provide ample storage, while the spa-like en suite flaunts a double sink vanity and twin showers. Your fully furnished terrace is an entertainer's dream with an extra-large saltwater pool and spa, cabana bath, large granite kitchen with gas and infrared burners, grand vent hood, side burner for seafood boils, and a bartending station with built-in blender, mini refrigerator and ice maker. The panoramic screened enclosure with a SWAT mosquito system allows for year-round enjoyment, while the patio with a beautiful Cypress wood ceiling provides for alfresco dining. Notables include impact glass, new first-floor air conditioner, security cameras throughout the property and single garage converted into a gym with air conditioning, mirror and rubber flooring. Highlights include a large upstairs loft with built-in cabinetry and a screened balcony to enjoy beautiful sunset views, Sonos system, large built-in safe and ample storage throughout the house. The exceptional home site offers back lawn fishing, programmable multicolor landscape lighting and beautiful shell paths. This home resides in a renowned, nature-inspired gated community with eight miles of hiking trails, kayaking, a waterfront restaurant, fitness center, tennis, pickleball and more. Only minutes from Old Naples pristine beaches, restaurants, yacht clubs and boutique shopping, this home offers a harmonious blend of serenity and sophistication.